martes, 20 de marzo de 2012

Dementia:

  • Alzheimer's Dementia
  • Vascular Dementia
  • Lewy Body Dementia
  • Parkinson's Disease
  • Normal Pressure Hydrocephalus
  • Huntington's Disease
  • Wernicke-Korsakoff's Syndrome
  • Creutzfeldt-Jakob Disease
  • Down's Syndrome

jueves, 15 de marzo de 2012

AWESOME website for studying EKGs!

http://meds.queensu.ca/courses/assets/modules/ts-ecg/ecg_index.html

Can you tell that I'm about to take my first ACLS class?

Adenosine (for fast heart rate):
  • Brand Name: Adenocard, Adenoscan 
  • Class: Antiarrhythmic
  • Indication: Supraventricular tachycardia (SVT), Paroxysmal SVT
  • Quick-acting, short-term therapy used to restore a normal heart rate and rhythm when there is SVT present
  • Always given when hooked up to EKG
  • Given intravenously (IV)
  • May be used to diagnose tachycardia
  • Will slow the heart rate when it is due to abnormal electrical pathway in the heart; will not work if the fast heart rate is due to other cause
  • May slow heart rate for a short time if you also have atrial fibrillation or atrial flutter
  • Side Effects:
    • Skin flushing in the face
    • Shortness of breath
    • Headache
    • Nausea
    • Chest pain or pressure


Supraventricular Tachycardia:
  • Supraventricular tachycardia (SVT): a fast heart rate that begins in the upper part of the heart (atria), above the ventricles
  • Normally, the heart's electrical system precisely controls the heart's rhythm; in this condition, abnormal electrical connections cause the heart to beat too fast.
  • Most supraventricular tachycardias result from abnormal electrical connections (bypass tracts) in the heart that short-circuit the normal electrical system and cause an increase in electrical activity.
  • Supraventricular tachycardia may cause an uncomfortable feeling that the heart is racing, pounding, and/or beating irregularly (palpitations). Additional symptoms include feeling dizzy or lightheaded, near-fainting or fainting (syncope), shortness of breath, chest pain, throat tightness, and sweating.
  • Some supraventricular tachycardias do not cause symptoms and may not need treatment. But if supraventricular tachycardia recurs, medicines or a procedure called catheter ablation may be needed to correct the abnormal heartbeat.



Catheter Ablation:
 

  • Catheter ablation (ab-LA-shun) is a medical procedure used to treat some types of arrhythmia (ah-RITH-me-ah). An arrhythmia is a problem with the rate or rhythm of the heartbeat.
  • During catheter ablation, a series of catheters (thin, flexible wires) are put into a blood vessel in your arm, groin (upper thigh), or neck. The wires are guided into your heart through the blood vessel.
  • A special machine sends energy to your heart through one of the catheters. The energy destroys small areas of heart tissue where abnormal heartbeats may cause an arrhythmia to start.
  • Catheter ablation often involves radiofrequency (RF) energy. This type of energy uses radio waves to produce heat that destroys the heart tissue. Studies have shown that RF energy works well and is safe.



Sources: 

Difference between NSAID and acetaminophen

So, I've always known that Aspirin and Tylenol weren't the same exactly, but I really never understood why. And when I did, I would often forget the difference. Here's the breakdown:

Non-steroidal anti-inflammatory drug (Aspirin):
  • reduces pain
  • reduces fever
  • reduces inflammation
  • causes stomach irritation/damage (biggest disadvantage of this medication)
    • inhibits the production of prostaglandins --> inhibits protection against acidity
    • prostaglandins
      • local hormones that transmit pain information to the brain
      • modulate hypothalamic thermostat
      • activate inflammatory response
      • stimulates constriction and clotting of platelets
      • involved with induction of labor
      • involved with GI tract (inhibits acid synthesis and increases secretion of protective mucus)
      • increases blood flow in kidneys
      • bronchoconstrictor (used for asthma)
  • reduces blood clot formation
    • Aspirin is the only NSAID with an antiplatelet effect 
  • Common types: Aspirin, Ibuprofen, Naproxen, Advil, Toradol, Motrin
    • These drugs differ in their mechanism of action, although they accomplish the same task

Acetaminophen/Paracetamol (Tylenol):
  • reduces pain
  • reduces fever
  • not indicated for anti-inflammatory purposes because it exhibits weak anti-inflammatory activity
  • does NOT reduce blood clot formation
  • better tolerated in those with gastric acid problems
  • Common types: Tylenol, Genapap, Feverall, Actamin, Altenol, Aminofen, Anacin Aspirin Free, Apra


Sources:
  • Aspirin is NOT acetaminophen
  • Acetaminophen = A for Analgesic!

Important note

When treating a patient with a heart condition (i.e. heart failure, heart attack) we have to remember not to give the patient nitroglycerin if they are taking any phosphodiesterase inhibitors (commonly used for erectile dysfunction). Phosphodiesterase inhibitors are peripheral vasodilators and can actually be used to treat hypertension, too. Nitroglycerin is a nitrate, given to treat patients with angina and is classified as a coronary vasodilator, meaning that it will increase the size of blood vessels leading directly to the heart. When you mix both nitroglycerin (nitrate) and phosphodiesterase inhibitors together, your patient is at risk of dropping their blood pressure to an extremely low level, possibly leading to a heart attack or stroke since not enough blood (aka oxygen) would effectively travel to the heart or to the brain.

This is a very useful bit of information to know -- especially useful for anyone interested in ICU, ED, or telemetry since there are many patients with heart conditions who may be taking a medication for erectile dysfunction.


Really interesting topics to look up

  • Ibuprofen (acetaminophen) vs. Acetaminophen (Tylenol)
  • Torsades de pointes
  • Indications of magnesium, atropine, epinephrine, dopamine
  • Summary of one research article in the American Journal of Critical Care
  • Summary of one research article in the American Journal of Nursing